『快乐就在你的基因里；不同种族容易感到快乐的程度也不同。』
The genetics of happiness：Transporter of delight
快乐也是遗传
Oct 15th 2011| from the Economist
THE idea that the human personality is a blank slate, to be written upon only by experience, prevailed for most of the second half of the 20th century. Over the past two decades, however, that notion has been undermined. Studies comparing identical with non-identical twins have helped to establish the heritability of many aspects of behavior, and examination of DNA has uncovered some of the genes responsible. Recent work on both these fronts suggests that happiness is highly heritable.
As any human being knows, many factors govern whether people are happy or unhappy. External circumstances are important: employed people are happier than unemployed ones and better-off people than poor ones. Age has a role, too: the young and the old are happier than the middle-aged. But personality is the single biggest determinant: extroverts are happier than introverts, and confident people happier than anxious ones.
That personality, along with intelligence, is at least partly heritable is becoming increasingly clear; so, presumably, the tendency to be happy or miserable is, to some extent, passed on through DNA. To try to establish just what that extent is, a group of scientists examined over 1,000 pairs of twins from a huge study on the health of American adolescents. In “Genes, Economics and Happiness”, a working paper from the University of Zurich’s Institute for Empirical Research in Economics, they conclude that about a third of the variation in people’s happiness is heritable. That is along the lines of, though a little lower than, previous estimates on the subject.
But while twin studies are useful for establishing the extent to which a characteristic is heritable, they do not finger the particular genes at work. One of the researchers, Jan-Emmanuel De Neve, has tried to do just that, by picking a popular suspect—the gene that encodes the serotonin-transporter protein, a molecule that shuffles a brain messenger called serotonin through cell membranes—and examining how variants of that gene affect levels of happiness.
Serotonin is involved in mood regulation. Serotonin transporters are crucial to this job. The serotonin-transporter gene comes in two functional variants—long and short. The long one produces more transporter-protein molecules than the short one. People have two versions (known as alleles) of each gene, one from each parent. So some have two short alleles, some have two long ones, and the rest have one of each.
The adolescents in Dr De Neve’s study were asked to grade themselves from very satisfied to very dissatisfied. Dr De Neve found that those with one long allele were 8% more likely than those with none to describe themselves as very satisfied; those with two long alleles were 17% more likely.
Which is interesting. Where the story could become controversial is when the ethnic origins of the volunteers are taken into account. All were Americans, but they were asked to classify themselves by race as well. On average, the Asian Americans in the sample had 0.69 long genes, the black Americans had 1.47 and the white Americans had 1.12.
That result sits comfortably with other studies showing that, on average, Asian countries report lower levels of happiness than their GDP per head would suggest. African countries, however, are all over the place, happinesswise. But that is not surprising, either. Africa is the most genetically diverse continent, because that is where humanity evolved. Black Americans, mostly the descendants of slaves carried away from a few places in west Africa, cannot possibly be representative of the whole continent.
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